Kyle and Rayanna -- SMA II Adult Stem Cell Patients

Kyle Knopes and Rayanna Seffens were accompanied by family as they traveled to Qingdao China to receive transplants of donated umbilical cord blood stem cells to treat symptoms of the genetic condition Spinal Muscular Atrophy Type 2 (SMA II). SMA is a neuro-muscular degenerative disorder leaving patients with a host of crushing symptoms. Kyle and Rayanna hoped that adult stem cell therapy using immuno-naive umbilical cord cells would help their systems overcome their genetic limitations.

Improvement statistics

Based on follow-up reports from 18 patients across 63 forms, here is the percentage who self-reported any improvement after treatment.

100%
Energy
reported improvement · N=14
94%
Limb muscle strength
reported improvement · N=17
93%
Hand control
reported improvement · N=14
88%
Movement in general
reported improvement · N=17
88%
Balance
reported improvement · N=17
88%
Trunk control
reported improvement · N=17
88%
Overall strength
reported improvement · N=16
88%
Trunk muscle strength
reported improvement · N=16
87%
Fine motor control
reported improvement · N=15
81%
Range of movement
reported improvement · N=16

About this data

Patients self-assess each symptom on a 5-point scale (Worse / No improvement / Small / Moderate / Significant) at follow-up checkpoints after treatment, comparing to their pre-treatment baseline. "Reported improvement" combines the small, moderate and significant buckets. Data is updated daily from our internal patient registry. As with any medical treatment, past results do not guarantee future outcomes — improvements vary from patient to patient.

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